en تخصصي Special گزارش مورد case report <span style="font-size:12pt"><span style="line-height:16.0pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:9.0pt">Multifocal epithelial hyperplasia (MEH) or Heck&rsquo;s disease is a rare, benign, non-common, self-limiting viral infection of the oral mucosa that is caused by human papillomavirus (HPV), especially subtype 13 or 32. The onset of the disease varies widely between different geographic regions and different races. A 45-year-old male patient was admitted to Department of Oral Medicine of Yazd Dental School for dental examination. Routine extra oral examination revealed numerous papules in the lips. The lesions were multiple, scattered papules that were interconnected in some areas and resembled an exophytic mass. Subsequently, the family history was positive and the clinical features conducted us to the diagnosis of the Focal Epithelial Hyperplasia. Since this disease is rare in the Iranian population and this case is the 19^th case in Iran, timely diagnosis and prevention of its transmission had the great importance. Therefore, promotion of dentists&#39; awareness towards diagnosis and appropriate referral to oral medicines specialists were recommended.</span></span></span></span><br> &nbsp; Focal Epithelial Hyperplasia, Human Papilloma Virus, Heck’s Disease, Oral, Hyperplasia 24 27 http://ijrabms.umsu.ac.ir/browse.php?a_code=A-10-212-2&slc_lang=en&sid=1 Maryam Jalili Sadrabad dr.njalli@gmail.com 10031947532846002585 10031947532846002585 No Assistant Professor, Oral Medicine Department, Dental School, Semnan University of Medical Sciences, Semnan, Iran. Shabnam Sohanian dr.sh.sohanian@gmail.com 10031947532846002586 10031947532846002586 Yes Assistant Professor, Oral and Maxillofacial Pathology Department, Dental School, Semnan University of Medical Sciences, Semnan, Iran. Sanaz Asadi asadisanaz1995@gmail.com 10031947532846002587 10031947532846002587 No Dentist, Zanjan, Iran Khatere Kheirollahi khaterekheirollahi@yahoo.com 10031947532846002588 10031947532846002588 No Assistant Professor, Oral Medicine Department, Dental School, Yazd University of Medical Sciences, Yazd, Iran.