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:: دوره 5، شماره 1 - ( 12-1397 ) ::
جلد 5 شماره 1 صفحات 30-35 برگشت به فهرست نسخه ها
Comparison of myocardial apoptosis in 21 and 90 days after birth in pups induced by maternal long term ethanol consumption
چکیده:   (74 مشاهده)
Background & Aims: This study was designed to assess and the cardiac apoptosis after the prenatal and early postnatal ethanol treatment in pups.
Materials and Methods: Pregnant Wistar rats treated with ethanol 4.5g/kg BW once per day from the seventh day of gestation (GD7) throughout lactation. Apoptotic cells, body wight, heart weight and their association on postnatal day 21 (PN-21) and postnatal day 90 (PN-90) was evaluated in male pups.
Results: The results showed that maternal ethanol consumption increased apoptotic cells, decreased heart weight, body weight, and HW/BW after 21 and 90 days of birth compared with the controls. It has found more apoptotic cells in 90 days after births compared with 21 days of age.
Conclusions: our findings revealed that maternal ethanol intake in pups decreased HW/BW ratio in part through apoptosis, which is more predominant in 90 days of age.
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نوع مطالعه: پژوهشي | موضوع مقاله: عمومى
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Shirpoor A, Nezami Majd F, Gaderi R, Naderi R. Comparison of myocardial apoptosis in 21 and 90 days after birth in pups induced by maternal long term ethanol consumption . RABMS. 2019; 5 (1) :30-35
URL: http://ijrabms.umsu.ac.ir/article-1-73-fa.html

Comparison of myocardial apoptosis in 21 and 90 days after birth in pups induced by maternal long term ethanol consumption . International Journal of Research in Applied and Basic Medical Sciences. 1397; 5 (1) :30-35

URL: http://ijrabms.umsu.ac.ir/article-1-73-fa.html



دوره 5، شماره 1 - ( 12-1397 ) برگشت به فهرست نسخه ها
International Journal of Research in Applied and Basic Medical Sciences
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