RT - Journal Article T1 - Study of serum lipid profile in patients with oral submucous fibrosis and oral squamous cell carcinoma and their comparative analysis JF - UMSU-Press YR - 2022 JO - UMSU-Press VO - 8 IS - 2 UR - http://ijrabms.umsu.ac.ir/article-1-185-en.html SP - 90 EP - 96 K1 - Oral Submucous Fibrosis K1 - Oral Squamous Cell Carcinoma K1 - Serum Lipid Profile AB - Background & Aims: The aim of this study was to evaluate serum lipid profile and compare their levels between the patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC). Materials & Methods: This descriptive study was done in two groups of patients; OSMF and OSCC patients. There were forty-five participants in each group. Serum samples obtained from centrifugation of 12 hour fasting blood samples was analyzed by fully automated analyzer Beckman coulter AU-680 for estimation of the lipid levels (cholesterol, triglycerides (TGL), and high‑density lipids (HDL)) using colorimetric methods. Low‑density lipid (LDL) values were obtained by calculation. Results: The comparison of lipid profile between Oral Submucous Fibrosis and Oral Carcinoma cases shows statistically significant results for TC, HDL and LDL. Conclusion: The change in lipid levels may have an early diagnostic or prognostic role in oral premalignant and malignant lesions. LA eng UL http://ijrabms.umsu.ac.ir/article-1-185-en.html M3 10.52547/rabms.8.2.90 ER -