AU - Shirpoor, Alireza AU - Nezami Majd, Faride AU - Gaderi, REZA AU - Naderi, Roya TI - Comparison of myocardial apoptosis in 21 and 90 days after birth in pups induced by maternal long term ethanol consumption PT - JOURNAL ARTICLE TA - UMSU-Press JN - UMSU-Press VO - 5 VI - 1 IP - 1 4099 - http://ijrabms.umsu.ac.ir/article-1-73-en.html 4100 - http://ijrabms.umsu.ac.ir/article-1-73-en.pdf SO - UMSU-Press 1 AB  - Background & Aims: This study was designed to assess and the cardiac apoptosis after the prenatal and early postnatal ethanol treatment in pups. Materials and Methods: Pregnant Wistar rats treated with ethanol 4.5g/kg BW once per day from the seventh day of gestation (GD7) throughout lactation. Apoptotic cells, body wight, heart weight and their association on postnatal day 21 (PN-21) and postnatal day 90 (PN-90) was evaluated in male pups. Results: The results showed that maternal ethanol consumption increased apoptotic cells, decreased heart weight, body weight, and HW/BW after 21 and 90 days of birth compared with the controls. It has found more apoptotic cells in 90 days after births compared with 21 days of age. Conclusions: our findings revealed that maternal ethanol intake in pups decreased HW/BW ratio in part through apoptosis, which is more predominant in 90 days of age. CP - IRAN IN - Department of Physiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran LG - eng PB - UMSU-Press PG - 30 PT - orginal article YR - 2019