en تخصصي Special پژوهشي orginal article <span style="font-size:12pt"><span style="line-height:16.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><i><span style="font-size:9.0pt">Background & Aims</span></i></b><b><span style="font-size:9.0pt">: </span></b>&nbsp;<span style="font-size:9.0pt">The thyroid gland, a small butterfly-shaped organ in the neck, regulates the body&rsquo;s metabolism. Disruptions in its function can lead to various health issues, including fatigue, weight changes, and cardiovascular problems. In hemodialysis patients, thyroid function is even more crucial. Hemodialysis, a treatment for kidney failure, filters waste and excess fluid from the blood, potentially affecting various bodily systems, including the endocrine system. This study examines the effect of thyroid function on hemodialysis.</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:16.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><i><span style="font-size:9.0pt">Materials & Methods</span></i></b><b><span style="font-size:9.0pt">:</span></b> <span style="font-size:9.0pt">In this descriptive-analytical study, dialysis patients were classified into three groups: hypothyroid, hyperthyroid, and euthyroid. The levels of thyroid and parathyroid hormones, serum electrolytes, clinical symptoms, laboratory results, and blood pressure of the patients in these groups were compared.</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:16.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><i><span style="font-size:9.0pt">Results</span></i></b><b><span style="font-size:9.0pt">:</span></b> <span style="font-size:9.0pt">There was no significant difference between the number of dialysis sessions and thyroid function. The serum calcium level was significantly higher in hypothyroid patients than in euthyroid and hyperthyroid patients. There were no significant differences in weight changes before and after dialysis considering the participants&rsquo; sex and age (<i>P = 0.227</i> and <i>P = 0.457</i>). Moreover, there were no significant differences in the number of dialysis sessions (<i>P = 0.508</i>), systolic (<i>P = 0.419</i>), and diastolic blood pressure (<i>P = 0.559</i>), or in the serum level of parathormone in patients with different thyroid functions (<i>P = 0.103</i>). However, the serum level of phosphorus was significantly higher in hyperthyroid patients than in normal patients and lower than in hypothyroid patients (<i>P = 0.049</i>). The hemoglobin concentration was higher in hyperthyroid patients than in other groups (<i>P = 0.021</i>).</span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:16.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><i><span style="font-size:9.0pt">Conclusion</span></i></b><b><span style="font-size:9.0pt">:</span></b> <span style="font-size:9.0pt">The changes in calcium, hemoglobin, and parathormone levels in hemodialysis patients with different thyroid function statuses showed significant differences. These differences are believed to be caused by high bone metabolism in dialysis patients. Evaluating these parameters in dialysis patients is recommended, highlighting the need for regular thyroid function screening among these patients.</span></span></span></span><span style="font-size:12pt"><span style="background:#d9d9d9"><span style="line-height:16.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-size:9.0pt"></span></span></span></span></span> Thyroid, Hemodialysis, Ferritin 299 309 http://ijrabms.umsu.ac.ir/browse.php?a_code=A-10-272-1&slc_lang=en&sid=1 Mahshad Rahimi mahshadrahimi906@gmail.com 10031947532846003220 0009-0003-6346-2990 No Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Hamid Reza Samimagham samimagham@yahoo.com 10031947532846003221 10031947532846003221 No Cardiovascular Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran: Bandar Abbas, Iran Ali Salimi Asl shervin7717@gmail.com 10031947532846003222 10031947532846003222 No Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Mohammadhosein Sheybani-Arani Mohammadhoseinsheybani@gmail.com 10031947532846003223 10031947532846003223 No Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Fatemeh Khajavi-Mayvan fatemehkhajavi18@gmail.com 10031947532846003224 10031947532846003224 No Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Elham Boushehri elhamboushehri@yahoo.com 10031947532846003225 10031947532846003225 No Assistant Professor, Department of Medical Education, School of Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Ladan Hajiabdolrassouli Lhajirassouli@gmail.com 10031947532846003226 10031947532846003226 No Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandarabbas, Iran Mitra Kazemi Jahromi mitra.kazemijahromi@gmail.com 10031947532846003227 10031947532846003227 Yes Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandarabbas, Iran