Comparison of traditional prenatal diagnosis procedures and Cell-Free DNA in maternal plasma as a new molecular approach for prenatal diagnosis

Babaei, Ghader; Naderi, Roya; Alipour, Shahriar; Gholizadeh-Ghaleh Aziz, Shiva

Volume 4, Issue 2 (October 2018) Journal of Research in Applied and Basic Medical Sciences 2018, 4(2): 108-118 | Back to browse issues page

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Babaei G, Naderi R, Alipour S, Gholizadeh-Ghaleh Aziz S. Comparison of traditional prenatal diagnosis procedures and Cell-Free DNA in maternal plasma as a new molecular approach for prenatal diagnosis. Journal of Research in Applied and Basic Medical Sciences 2018; 4 (2) :108-118
URL: http://ijrabms.umsu.ac.ir/article-1-72-en.html

Comparison of traditional prenatal diagnosis procedures and Cell-Free DNA in maternal plasma as a new molecular approach for prenatal diagnosis

Ghader Babaei

, Roya Naderi

, Shahriar Alipour

, Shiva Gholizadeh-Ghaleh Aziz ^*

Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran , doctorgholizadeh@gmail.com

Abstract: (2661 Views)

Cell-free DNA (cfDNA) is a moderately novel method with an exponential expansion in uses for a wide range of applications. The clinical services of these new techniques will be estimated by the scientist in the field via the newest case studies. Non-invasive detection of cell-free DNA has the potential to impact treatment regimens and clinical protocols. cfDNA will manage the standard of care in transplant medicine, oncology, and cardiovascular disease. This field is appearing as one of the most exciting and promising areas of medicine and other sciences and can make a huge influence on prenatal care. The aim of this review is to present potential and application of Cell-Free DNA in prenatal diagnosis.

Keywords: Cardiovascular disease, Cell-Free DNA, Prenatal diagnosis, Non-invasive

Full-Text [PDF 423 kb] (2206 Downloads)

Type of Study: review article | Subject: Special