Volume 11 - Issue 4 (November 11-2025 - Serial : 31) - 12 Article(s)
🔬 RABMS Publishes 12 New Contributions Across Medical and Biomedical Sciences
Research in Applied and Basic Medical Sciences (RABMS) is pleased to announce a new issue featuring 12 contributions covering anesthesia, neuroscience, toxicology, pharmacology, public health, genetics, diabetes, infectious diseases, and emerging areas of medical science.
🩺 Anesthesia & Neurological Research
A narrative review examines the complications and risks of general and regional anesthesia in orthopedic surgery, emphasizing individualized anesthetic choices according to surgical procedures and patient characteristics.
Another study investigates the effects of prolonged orthostasis on EEG activity, reporting changes in beta-wave activity and the alpha/beta ratio and highlighting considerations for orthostatic tolerance testing.
🌿 Medicinal Plants & Toxicology
Two experimental studies explore the pharmacological potential and safety of African medicinal plants. Research on Guiera senegalensis examines its neurobehavioral effects alongside evidence of hepatotoxicity and nephrotoxicity following subacute exposure. Another study evaluates the phytochemical, analgesic, and acute toxicity profiles of Moringa oleifera, Anogeissus leiocarpus, and Commiphora africana.
💊 Public Health & Drug Use
A community-based study reports a high prevalence of over-the-counter drug use among traders in Nigeria, particularly analgesics, antibiotics, and antimalarials, highlighting the importance of responsible self-medication.
Research from Central India examines drug utilization patterns among patients with type 2 diabetes, finding frequent use of metformin-based combination therapy and highlighting the importance of prescription monitoring and individualized treatment.
🧬 Genetics, Reproductive Health & Emerging Therapies
The issue includes research on the CTLA-4 +49 A/G polymorphism in diabetic retinopathy, examining its association with cardiovascular risk factors.
An experimental study investigates whether probiotic supplementation can mitigate reproductive effects associated with light pollution, reporting improvements in sperm parameters, inflammatory markers, and DNA damage in treated animals.
Another study evaluates a newly synthesized compound with antibacterial activity against E. coli and S. aureus, providing preliminary evidence for further investigation of novel antibacterial agents.
🍎 Nutrition & Health Promotion
A school-based intervention examines the effect of nutrition education on dietary diversity among adolescents in Nigeria. Although improvements in knowledge and dietary diversity were observed, the findings indicate that longer interventions and broader household and school support may be needed.
🐝 Clinical Case Reports & Toxicological Perspectives
A case series highlights multiple organ dysfunction following massive honeybee envenomation, including acute kidney and liver injury and neurological complications, emphasizing the need for urgent medical evaluation following extensive stings.
The issue also features a forward-looking review of the exposome, exploring how environmental exposures, lifestyle, analytical chemistry, computational methods, and toxicology can be integrated to better understand complex diseases.
🔬 12 Articles | 🩺 Clinical Research | 🌿 Natural Products | 💊 Pharmacology | 🧬 Genetics | 🌍 Public Health
Together, these contributions reflect the multidisciplinary scope of RABMS and provide perspectives ranging from experimental laboratory research and clinical case reports to public health and emerging approaches in medical science.
Volume 11 - Issue 3 (August 8-2025 - Serial : 30) - 12 Article(s)
🧬 RABMS Presents 12 New Contributions in Experimental, Clinical, and Applied Medical Sciences
Research in Applied and Basic Medical Sciences (RABMS) is pleased to announce the publication of a new issue featuring 12 research contributions spanning experimental, clinical, pharmaceutical, educational, and applied medical sciences.
🔬 12 Articles | 🧪 Experimental Research | 🩺 Clinical Science | 💊 Pharmaceutical Research | 👩⚕️ Health & Nursing | 🌍 Public Health
This issue brings together research investigating medicinal plants, toxicology, pharmacology, reproductive health, occupational exposure, renal and prostate pathology, pharmaceutical formulation, sports performance, congenital anomalies, and infectious diseases.
🌿 Natural Products & Medicinal Plant Research
The issue features several studies exploring the biological effects and potential therapeutic applications of natural products.
A toxicological and histopathological study evaluates extracts from five medicinal plants used as potential protectants against insect infestation, examining their effects on liver and kidney function and tissue structure in BALB/c mice.
Another experimental study investigates the nutritional, phytochemical, and hypolipidemic properties of four medicinal plants traditionally used in Southern Nigeria. The study reports lipid-lowering and hepatoprotective effects in an animal model, highlighting the potential of these plants for further investigation.
🌱 From traditional medicine to experimental evidence:
The findings contribute to ongoing research into the safety and therapeutic potential of medicinal plants.
🧪 Toxicology, Pharmacology & Experimental Medicine
Research in experimental pharmacology and toxicology is strongly represented in this issue.
One investigation examines the subchronic effects of ethinylestradiol and levonorgestrel on hematological parameters, cytokine signaling, and oxidative stress in Wistar rats.
Another study evaluates the effects of dextromethorphan exposure on testicular and epididymal structure and investigates whether the antioxidants rutin and quercetin can contribute to recovery from the observed changes.
The issue also includes research on nandrolone decanoate-induced prostate changes, documenting alterations in prostate weight and histopathological features following exposure.
🏭 Occupational & Environmental Health
A study of plasma lead levels and oxidative stress markers in petroleum workers provides insight into the biological effects associated with occupational exposure.
The research identifies differences in lead levels and antioxidant-related parameters between exposed workers and controls, emphasizing the importance of occupational monitoring, exposure control, and preventive health strategies.
⚠️ Occupational exposure matters:
Biomonitoring and preventive interventions can play an important role in protecting workers from long-term health consequences.
🩺 Kidney Health & Protective Strategies
The issue also addresses renal toxicity and potential protective interventions.
One experimental study investigates the effects of sodium fluoride exposure on kidney morphology, histology, and biochemical markers of renal function, while examining whether vitamin E can mitigate these changes.
The findings provide experimental evidence concerning fluoride-associated renal alterations and the potential protective role of antioxidant supplementation.
💊 Pharmaceutical Sciences & Drug Compatibility
In the field of pharmaceutical sciences, a physicochemical investigation examines the compatibility of amoxicillin and lactose in the solid state.
Using techniques including Fourier-transform infrared spectroscopy and differential scanning calorimetry, the study identifies incompatibility between the drug and lactose under the investigated conditions.
💡 Why it matters:
Drug–excipient compatibility is an important consideration during pharmaceutical formulation and pre-formulation studies because interactions may influence drug stability and dosage-form performance.
👩⚕️ Nursing Education & Clinical Decision-Making
The issue extends beyond laboratory research to health-professions education.
A quasi-experimental study conducted at Urmia University of Medical Sciences investigates the effect of evidence-based education on clinical decision-making among nursing students.
Students who participated in the educational intervention demonstrated improved clinical decision-making scores following the intervention, highlighting the importance of evidence-based education in developing clinical competencies and supporting safe, high-quality patient care.
🏆 Sports Science & Athletic Performance
In sports and exercise science, researchers investigate the combined effects of short-term caffeine supplementation and post-activation potentiation on fatigue and anaerobic performance among professional Wushu athletes.
The study reports improvements in measures of anaerobic power following the interventions, contributing to research on strategies that may help optimize athletic performance.
🏃 Performance & science:
The study connects nutritional supplementation and exercise strategies with measurable aspects of athletic performance.
👶 Congenital Anomalies & Developmental Medicine
The issue also presents a case series on amniotic band syndrome, an uncommon condition associated with a wide range of congenital abnormalities.
Six fetal cases are described, demonstrating different patterns of limb, craniofacial, and body-wall abnormalities. The report illustrates the diverse clinical and anatomical manifestations of the condition and emphasizes its consideration when multiple congenital anomalies are identified.
🦠 Infectious Diseases & Diagnostic Challenges
The issue concludes with “Unveiling the Complexity of Campylobacter Bacteremia,” presenting a case of Campylobacter coli bacteremia in an older man with diabetes who developed bloodstream infection without preceding diarrhea.
The case highlights the potential for Campylobacter infection to present beyond its more familiar gastrointestinal manifestations and emphasizes the importance of accurate laboratory identification and pathogen-targeted treatment.
🌍 A Diverse Issue Reflecting Modern Biomedical Research
The 12 contributions in this issue demonstrate the breadth and interdisciplinary nature of contemporary biomedical research.
From medicinal plants and experimental toxicology to pharmaceutical sciences, occupational health, nursing education, sports science, congenital anomalies, and infectious diseases, the issue brings together diverse perspectives and research approaches.
🔬 Exploring science.
🩺 Supporting clinical knowledge.
🌱 Advancing health research.
RABMS invites researchers, clinicians, healthcare professionals, academics, and students to explore the newly published articles and engage with the diverse research presented in this issue.
Volume 11 - Issue 2 (May 5-2025 - Serial : 29) - 12 Article(s)
RABMS Publishes a New Issue Featuring 12 Contributions Across Biomedical and Health Sciences
Research in Applied and Basic Medical Sciences (RABMS) is pleased to announce the publication of its latest issue, featuring 12 research contributions addressing a diverse range of topics across biomedical and health sciences.
The new issue brings together research spanning clinical medicine, anatomy, pathology, forensic sciences, nutrition, endocrinology, infectious diseases, toxicology, reproductive health, and adolescent health. Collectively, these publications reflect the journal’s commitment to disseminating research that connects fundamental scientific knowledge with clinically and socially relevant health questions.
Highlights from the New Issue
The issue opens with research addressing physical activity and mental health among adolescents during the COVID-19 pandemic. One study investigates autonomy-supportive physical education and its association with physical activity, harmonious passion, loneliness, and mental vitality among adolescent girls.
In the field of anatomy and interventional medicine, a detailed investigation of the coronary venous system examines anatomical variations of the Thebesian and Vieussens valves and the great cardiac vein, providing information relevant to coronary venous catheterization and invasive cardiology.
The issue also includes research on diabetes and reproductive health, with a case-control study investigating semen quality among Sudanese men with type 2 diabetes mellitus. Another study explores the relationship between telomere length, vitamin D status, and glycaemic parameters, contributing to research on cellular aging and diabetes.
Two contributions focus on anatomical and forensic applications. A study among the Tiv population of Benue State evaluates lower-jaw measurements for sex and anthropological identification, while a case report documents a rare congenital distal tibiofibular synostosis and discusses its potential clinical relevance.
The latest issue also addresses important public health and nutritional challenges. A narrative review examines the complex causes and consequences of malnutrition in Nigeria, including food insecurity, poverty, climate-related factors, health challenges, and the need for locally appropriate strategies to strengthen nutritional resilience.
In pathology and diagnostic medicine, an institutional study examines the clinicopathological characteristics and immunohistochemical profiles of salivary gland tumors. Another study investigates biopsy sites and histopathological grading for Helicobacter pylori infection among patients presenting with dyspepsia, highlighting the distribution of infection across different gastric regions.
Clinical research in the issue further examines electrocardiographic changes following laparoscopic cholecystectomy in patients with acute cholecystitis and no previous cardiac disease. The findings provide additional clinical observations regarding transient ECG alterations in this patient population.
The issue also features an experimental investigation into the effects of sodium metabisulfite exposure in Wistar rats, examining hematological parameters, liver enzymes, and structural changes in the liver and spleen.
Finally, a randomized clinical trial in pediatric oncology compares cefepime monotherapy with ceftriaxone–amikacin combination therapy for children with chemotherapy-induced fever and neutropenia, examining clinical outcomes including hospitalization, fever, and antimicrobial treatment escalation.
Advancing Biomedical Research Through Diverse Perspectives
The breadth of the newly published articles illustrates the interdisciplinary nature of contemporary biomedical research. From basic anatomical and experimental investigations to clinical studies and public health research, the issue addresses questions relevant to researchers, healthcare professionals, and the wider scientific community.
RABMS remains committed to providing a platform for the dissemination of rigorous research across the biomedical and health sciences and to promoting communication among researchers working across diverse scientific disciplines.
Readers are invited to explore the full articles in the latest issue of RABMS and engage with the research and findings presented by contributing authors from different scientific and clinical backgrounds.
Volume 11 - Issue 1- 2025
Assessment of immune response in ICU admitted SARS-CoV-2 patients from Kashmir, North India
The study examined lymphocyte subpopulations in ICU-admitted COVID-19 patients to understand immune dysregulation. It found increased NLR, T-cell activation, T-cytotoxic exhaustion, and reduced B cells as markers of disease severity and poor outcomes.
The CD4 cell level as a predictive factor for the outcome severity and prognosis of patients with COVID-19
The study examined the link between CD4+ T-cell levels and COVID-19 severity, finding that lower CD4 counts are strongly associated with worse prognosis. The correlation with higher CRP suggests CD4 depletion as a key marker for predicting outcomes, highlighting its potential role in managing severe cases.
Advancements in MRI radiomics for hepatocellular carcinoma: a narrative review
Hepatocellular carcinoma (HCC) is a major global health concern with limited preoperative diagnostic tools. MRI radiomics offers a noninvasive approach to predict outcomes and aid personalized treatment decisions. Further research is needed for its clinical integration in HCC management.
Biochemical and histological assessment of the hepatoprotective effects of Bryophyllum pinnatum leaf extract in Ketamine-induced liver toxicity in male Wistar rats
This study explored the hepatoprotective effects of Bryophyllum pinnatum against ketamine-induced liver toxicity in Wistar rats. The extract demonstrated promising benefits by normalizing liver biomarkers and promoting histological recovery, suggesting its potential for therapeutic use in liver disorders and warranting further research.
Cardiovascular diseases and ischemic stroke: the importance of embolism and thrombosis
This study highlights CHF as an independent risk factor for AIS and emphasizes the clinical significance of monitoring immunological processes over RBC count and HCT levels. Key factors like age, RBC count, anemia, cholesterol, lipoproteins, and blood glucose may aid in differentiating thrombotic and embolic strokes in AIS patients with CHF.
Aphrodisiac activity of ethanolic root extracts of Acacia pycnantha (Golden Wattle) in healthy male Wistar rats
This study investigates the aphrodisiac effects of Acacia pycnantha in male Wistar rats, revealing its ability to enhance sexual behavior, elevate serum-free testosterone levels, and increase serum calcium concentrations, highlighting its potential as a natural aphrodisiac.
Secondary osteoarthritis due to alkaptonuria: a case report
Alkaptonuria is a rare genetic disorder caused by homogentisate 1,2-dioxygenase deficiency, leading to homogentisic acid accumulation. It manifests as homogentisic aciduria, ochronosis, and progressive arthritis, often causing secondary osteoarthritis. Early diagnosis and a multidisciplinary approach are essential for reducing morbidity and improving quality of life.
Molecular surveillance of artemisinin resistance-linked PFK13 gene polymorphisms in Adamawa State, Nigeria
This study investigated Plasmodium falciparum artemisinin resistance by analyzing Pfk13 polymorphisms in clinical isolates from Adamawa State, Nigeria. The absence of Pfk13 mutations suggests parasite sensitivity to artemisinin, though the detected A578S mutation requires further study. Ongoing surveillance is essential to monitor and prevent drug resistance.
Oxidative stress pattern of patients with abnormal thyroid function in Southern Nigeria
This study evaluated antioxidants and oxidative stress in individuals with abnormal thyroid hormone levels in Irrua, Edo State. The results indicate that hyperthyroidism induces oxidative stress, potentially contributing to disease development and other related conditions, regardless of gender.
Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
This study assessed vaccine hesitancy for the COVID-19 booster dose among undergraduate medical students in Puducherry, identifying socio-demographic, experiential, and perceptual factors as key influences. Addressing these through targeted education, clear communication, and support at vaccination sites can enhance vaccine uptake and help control the pandemic. Further research on diverse populations is needed to evaluate the effectiveness of these strategies.
Electrophysiological analysis of the upward and downward phases of squat and lying leg raise work-out
This study examined the effects of the upward and downward phases of squats and lying leg raises on electroencephalograms (EEG) and electrocardiograms (ECG) in healthy male individuals. It found that the downward phase of squats resulted in higher beta wave frequency, lower alpha wave frequency, and greater cortical activation compared to the downward phase of lying leg raises, providing insights into how different exercises affect brain activity.
A retrospective study of serous ovarian tumour with IHC correlation: a three-year study
This retrospective study analyzed the clinicopathological features of serous ovarian tumors and their correlation with immunohistochemical (IHC) markers to enhance diagnostic accuracy. It found that factors like increasing age, postmenopausal status, bilaterality, and complex morphology were linked to malignancy, and highlighted the importance of IHC markers such as WT1, CK7, CK20, CEA, and CA125 in diagnosing and differentiating these tumors.
Issue 2. 2024 News
A study reveals optimal angles at 20° and 30° improve dose conformity and OAR sparing, guiding clinical decisions in radiation therapy.
Vitamin D and AMH in PCOS:
Research indicates no significant difference in Vitamin D levels between PCOS patients and controls, with a weak positive correlation between Vitamin D and AMH levels.
Emerging Resistance in UTI Pathogens:
A significant study from a tertiary care hospital highlights the rise of multidrug-resistant bacteria in UTIs, emphasizing the critical need for ongoing monitoring of antimicrobial susceptibility
Prophylactic Amiodarone in Valve Surgery:
A pivotal study shows that a single dose of amiodarone significantly reduces post-operative atrial fibrillation, leading to shorter ICU and hospital stays.
Hyoscine vs. Promethazine in Labor:
Meta-analysis shows Hyoscine N-butyl bromide reduces labor duration, especially in multiparous women, while Promethazine shows no significant effect.
Tonometer Comparison in Glaucoma Detection:
Study confirms all tonometers correlate well with the Goldmann standard, crucial for early glaucoma diagnosis in patients aged 30-75, including those with diabetes and hypertension.
Fludrocortisone’s Role in Fertility:
A study shows fludrocortisone enhances endometrial receptivity by modulating gene expression, potentially improving fertility treatments.
Biochemical Predictors of Diabetic Neuropathy:
A study underscores the importance of regular screening for glycosylated hemoglobin, lipid profile, and creatinine in predicting neuropathy in diabetic patients.
Issue 3. 2023 News
The news related to the articles published in this issue are as follows:
Issue 2. 2023 News
The news related to the articles published in this issue are as follows:
Effect of a significant deficiency in some antioxidants on semen parameters in cases of male infertility in Diyala Province, Iraq: Biologists from Iraq examined the effect of a significant deficiency in some antioxidants on semen parameters in cases of male infertility in Diyala Province, Iraq. They measured the levels of serum ascorbate, tocopherol, selenium, and zinc in 47 infertile men and 21 healthy men, and compared them with the sperm count, motility, and morphology. They found that the deficiency of antioxidants was associated with a decrease in semen quality and suggested that increasing antioxidant levels may help improve male infertility.
Spectrum of gastrointestinal malignancies in a rural tertiary care center: Gastroenterologists from India investigated the spectrum of gastrointestinal malignancies in a rural tertiary care center. They studied 1000 patients diagnosed with gastrointestinal cancer and reported the type, location, symptoms, risk factors, and treatment outcomes. They found that stomach cancer, colorectal cancer, and small bowel cancer were the most common types of gastrointestinal cancer, and Helicobacter pylori infection, family history, smoking, and alcohol consumption were the main risk factors. They concluded that gastrointestinal cancers in rural areas have different patterns and prevalence compared to urban areas, and they require prevention and early detection strategies.
C-Reactive protein and chest x-ray morphology in COVID-19 patients: Pathologists from India examined the relationship between C-reactive protein (CRP), an inflammation marker, and chest x-ray morphology in COVID-19 patients. They studied 100 patients hospitalized due to COVID-19 infection and measured the serum levels of CRP and their chest radiographic findings. They found that the CRP levels were significantly higher in COVID-19 patients compared to healthy individuals and were associated with the severity and extent of lung damage. They suggested that CRP can be used as a simple and cost-effective marker for the diagnosis, monitoring, and prediction of COVID-19 patients.
Formulation of a broad-spectrum nanoemulsion from thymus vulgaris essential oil with enhanced antimicrobial activity against problematic gram-negative bacteria and fungi: Microbiologists from India developed a nanoemulsion with a broad spectrum of thymus vulgaris (thyme) essential oil, which exhibited increased antimicrobial activity against problematic gram-negative bacteria and fungi. They evaluated the properties of the nanoemulsion using physicochemical methods and measured its antimicrobial activity against several antibiotic-resistant bacterial strains and fungi. They found that the nanoemulsion had good stability, small particle size, high transparency, and antimicrobial activity against a wide range of microorganisms. Despite the presence of essential oil, it had low toxicity.
Estimation of Morphometric Variations in Greater Sciatic Notch of Human Hip Bones: An Anatomical Study: Researchers from India measured the differences between male and female skull bones based on the shape and size of the greater sciatic notch, a bony indentation behind the ear. They used a statistical method to quantify these variations. They found that this indentation is larger and more angled in males, and it can be used with high accuracy to determine the sex of unidentified bones.
A comparison of the Effects of Low and High Doses of Corticosteroids on Recovery of the Patients with Covid-19: Physicians from Iran compared the effects of low and high doses of corticosteroids on the recovery of patients with COVID-19. They studied 100 hospitalized patients with severe COVID-19 infection and divided them into two groups: one group receiving low dose (1 to 1.5 milligrams per kilogram of body weight per day) and another group receiving high dose (5 to 10 milligrams per kilogram of body weight per day) of corticosteroids. They compared the outcomes of mortality, need for mechanical ventilation, development of acute respiratory distress syndrome (ARDS), and duration of hospitalization between the two groups. They found that high-dose corticosteroid administration was associated with increased mortality, need for mechanical ventilation, development of ARDS, and longer hospitalization time. They recommended caution against the use of high-dose corticosteroids in the treatment of severe COVID-19 patients.
Platelet Indices in Acute Coronary Syndrome Patients: Researchers from Iran investigated the relationship between platelet indices and other factors in determining the risk of acute coronary syndrome (ACS). The results showed that platelet count did not show significant changes or relation with ACS patients, while mean platelet volume (MPV) was not significantly higher in the myocardial infarction (MI) group compared to the unstable angina (UA) group. However, higher MPV values were associated with a higher mortality rate. Elevated platelet distribution width (PDW) was significantly correlated with both MI groups and mortality, suggesting its potential as a prognostic factor for ACS.
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