XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mohammadian M, Feizollah zadeh S, Rasuli J, Rasouli M A, Alizadeh M. The Effect of Ramadan Fast on Serum liver Enzyme Levels in Iranian Adults. Journal of Research in Applied and Basic Medical Sciences 2021; 7 (2) :104-107
URL: http://ijrabms.umsu.ac.ir/article-1-100-en.html
Urmia University of Medical Sciences , Urmia , Iran , sadeghimmune@yahoo.com
Abstract:   (2563 Views)
Background & Aims:  Ramadan fasting has numerous health benefits. Nevertheless, its beneficial role on liver function was evaluated by limited studies and different findings were recorded. So, this study aimed to define the effect of Ramadan Fasting on liver enzyme levels in Iranian healthy individuals.
Materials & Methods: Seventy healthy adult men without history of liver diseases and current usage of any medication affecting the liver were involved in the present survey. Anthropometric parameters and liver function tests were measured before and after Ramadan. The biochemical parameters including liver enzymes Aspartate aminotransferase (ALT), Alanine Aminotransferase (ALT) and Alkaline Phosphatase (ALP) were evaluated before and after Ramadan by the standard enzymatic method.
Results: A decrease was observed in mean level of all liver enzymes. Indeed, the significant mean decrease in the ALT values in the post-Ramadan analyses was observed in the pre-Ramadan (p < 0.01). The values of ALP and AST decreased at the end of the study in the post-Ramadan group versus pre-Ramadan, but mean of the changes did not reach a significant level.
Conclusion: The changes in the concentrations of liver enzymes showed remarkable differences between groups. These data confirmed that Ramadan Fasting improved liver function in healthy adults and might be valuable in the management of liver function.
Full-Text [PDF 240 kb]   (1137 Downloads)    
Type of Study: orginal article | Subject: General

References
1. Nasiri J, Kheiri S, Khoshdel A, Boroujeni AJ. Effect of Ramadan Fast on Liver Function Tests. Iran J Med Sci 2016;41(5):459-60. [address]
2. Azizi F, Rasouli H. Serum glucose, bilirubin, calcium, phosphorus, protein and albumin concentrations during Ramadan. Med J Islam Repub Iran 1987;1:38-41. [address]
3. Mohamed SY, Emara MH, Hussien HI, Elsadek HM. Changes in portal blood flow and liver functions in cirrhotics during Ramadan fasting in the summer; a pilot study. Gastroenterol Hepatol Bed Bench 2016;9(3):180-8. [PubMed]
4. Farrokhseresht R, Ariannia S, Hadizadeh Neisanghalb R. Effect of fasting on liver enzyme in patients using methotrexate; cohort study. Acta Health Medica 2016; 1(4);80-3. [DOI:10.19082/ah80]
5. Shehab A, Abdulle A, El Issa A, Al Suwaidi J, Nagelkerke N. Favorable changes in lipid profile: the effects of fasting after Ramadan. PLoS One 2012;7(10):e47615. [DOI:10.1371/journal.pone.0047615] [PMID] [PMCID]
6. Zadegan N, Atashi M, Naderi G, Baghai A, Asgary S, et al. The Effect Of Fasting In Ramadan on the Values and Interrelations Between Biological, Coagulation and Hematological Factors. Ann Saudi Med 2000; 20: 5-6. [DOI:10.5144/0256-4947.2000.377] [PMID]
7. Khaled M, Belbraouet S. Ramadan Fasting Diet Entailed a Lipid Metabolic Disorder Among Type 2 Diabetic Obese women. Am J Appl Sci 2009: 6(3): 471-7
8. Saleh S, Elsharouni A, Cherian B, Mourou M. Effects of Ramadan fasting on Waist Circumference, Blood Pressure, Lipid Profile, and Blood Sugar on a Sample of Healthy Kuwaiti Men and Women. Mal J Nutr 2005;11(2): 143-50. [Google Scholar]
9. Grundy SM, Denke MA. Dietary influences on serum lipids and lipoproteins. J Lipid Res 1990; 31: 1149-72. [DOI:10.1016/S0022-2275(20)42625-2]
10. Angel JF, Schwartz NE. Metabolic changes resultingfrom decreased meal frequency in adult male Muslims during the Ramadan fast. Nutr Rep Int 1975; 11: 29-38.
11. Mohammed Z. The Influence of Ramadan fasting on some hematological and biochemical parameters in healthy adult males. Iraqi National J for Nursing Specialties 2011;24:45-51.
12. Naveen GH, Shetty P, Goutham M P, Ganesh P B, ChethanR, Sangram P. Effect of Naturopathic Based Fasting Therapy on Liver Enzymes, Electrolytes, Fasting Blood Glucose, Weight And Perceived Stress Among Healthy Individuals -A Randomized Controlled Trial. International Journal of Yoga and Allied Sciences 2014; 3(2). [address]
13. Fahrial Syam A, Suryani Sobur C, Abdullah M, Makmun D. Ramadan Fasting Decreases Body Fat but Not Protein Mass. Int J Endocrinol Metab 2016;14(1):e29687. [DOI:10.5812/ijem.29687] [PMID] [PMCID]
14. Norouzy A, Salehi M, Philippou E, Arabi H, Shiva F, Mehrnoosh S, et al. Effect of fasting in Ramadan on body composition and nutritional intake: a prospective study. J Hum Nutr Diet 2013; 1:97-104. [DOI:10.1111/jhn.12042] [PMID]
15. Lessan N, Ali T. Energy Metabolism and Intermittent Fasting: The Ramadan Perspective. Nutrients 2019;11(5):1192. [DOI:10.3390/nu11051192] [PMID] [PMCID]
16. Elfert AA, AbouSaif SA, Kader NAA, AbdelAal E, Elfert AY, Moez ATA, et al. A Multicenter Pilot Study of the Effects of Ramadan Fasting on Patients with Liver Cirrhosis. Tanta Med J 2011;6:33-25. [Google Scholar]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Research in Applied and Basic Medical Sciences

Designed & Developed by : Yektaweb