COVID-19 in a Patient with Newly Diagnosed Chronic Lymphocytic Leukemia (CLL): A Case Report

Gandomi-Mohammadabadi, Alireza; Divsalar, Farshad; Taram, Saman; Kateb, Zahra; Montazer, Fatemeh; Farbod, Yasaman; Tabibzadeh dezfooli, Seyedamir; Abbasi, ata; abbasi, Mohammad Amin

doi:10.52547/rabms.7.1.26

Volume 7, Issue 1 (3-2021) Journal of Research in Applied and Basic Medical Sciences 2021, 7(1): 26-30 | Back to browse issues page

‎ 10.52547/rabms.7.1.26

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Gandomi-Mohammadabadi A, Divsalar F, Taram S, Kateb Z, Montazer F, Farbod Y, et al . COVID-19 in a Patient with Newly Diagnosed Chronic Lymphocytic Leukemia (CLL): A Case Report. Journal of Research in Applied and Basic Medical Sciences 2021; 7 (1) :26-30
URL: http://ijrabms.umsu.ac.ir/article-1-138-en.html

COVID-19 in a Patient with Newly Diagnosed Chronic Lymphocytic Leukemia (CLL): A Case Report

Alireza Gandomi-Mohammadabadi

, Seyedamir Tabibzadeh dezfooli

, Ata Abbasi

, Mohammad Amin Abbasi ^*

Firoozabadi Clinical Research Development Unit (FCRDU), Iran University of Medical Sciences (IUMS), Tehran, Iran. , Amin.abbasi1314@gmail.com

Abstract: (2588 Views)

Chronic lymphocytic leukemia (CLL) is one of the most common hematologic neoplasms leading to immunosuppression. It is characterized by absolute lymphocytosis with clonality of mature B cells. Therefore, they are vulnerable to various infections especially COVID-19. Little is known about the COVID-19 infection when it unmasks CLL.
We reported a 90-year-old man who presented with signs and symptoms of anorexia, weakness, and loss of consciousness, and lymphocytosis which in further workup COVID-19 confirmed with real-time PCR. Due to lymphocytosis, peripheral blood smear (PBS) and flow cytometry were performed and CLL was diagnosed. His lymphocyte count increased to 1.5-fold during hospitalization. The patient recovered after 11 days as the symptoms were alleviated.
Lymphocytosis is an unexpected finding in patients diagnosed with COVID-19 infection, and an increase in lymphocytes may indicate other conditions. In these cases, secondary causes of lymphocytosis, such as malignancy or other infections, should be considered

Keywords: Coronavirus, COVID-19, Leukemia, Lymphocytic, Chronic

Full-Text [PDF 720 kb] (1236 Downloads)

Type of Study: case report | Subject: Special

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