Research in Applied and Basic Medical Sciences (RABMS) is pleased to announce a new issue featuring 12 contributions covering anesthesia, neuroscience, toxicology, pharmacology, public health, genetics, diabetes, infectious diseases, and emerging areas of medical science.
A narrative review examines the complications and risks of general and regional anesthesia in orthopedic surgery, emphasizing individualized anesthetic choices according to surgical procedures and patient characteristics.
Another study investigates the effects of prolonged orthostasis on EEG activity, reporting changes in beta-wave activity and the alpha/beta ratio and highlighting considerations for orthostatic tolerance testing.
Two experimental studies explore the pharmacological potential and safety of African medicinal plants. Research on Guiera senegalensis examines its neurobehavioral effects alongside evidence of hepatotoxicity and nephrotoxicity following subacute exposure. Another study evaluates the phytochemical, analgesic, and acute toxicity profiles of Moringa oleifera, Anogeissus leiocarpus, and Commiphora africana.
A community-based study reports a high prevalence of over-the-counter drug use among traders in Nigeria, particularly analgesics, antibiotics, and antimalarials, highlighting the importance of responsible self-medication.
Research from Central India examines drug utilization patterns among patients with type 2 diabetes, finding frequent use of metformin-based combination therapy and highlighting the importance of prescription monitoring and individualized treatment.
The issue includes research on the CTLA-4 +49 A/G polymorphism in diabetic retinopathy, examining its association with cardiovascular risk factors.
An experimental study investigates whether probiotic supplementation can mitigate reproductive effects associated with light pollution, reporting improvements in sperm parameters, inflammatory markers, and DNA damage in treated animals.
Another study evaluates a newly synthesized compound with antibacterial activity against E. coli and S. aureus, providing preliminary evidence for further investigation of novel antibacterial agents.
A school-based intervention examines the effect of nutrition education on dietary diversity among adolescents in Nigeria. Although improvements in knowledge and dietary diversity were observed, the findings indicate that longer interventions and broader household and school support may be needed.
A case series highlights multiple organ dysfunction following massive honeybee envenomation, including acute kidney and liver injury and neurological complications, emphasizing the need for urgent medical evaluation following extensive stings.
The issue also features a forward-looking review of the exposome, exploring how environmental exposures, lifestyle, analytical chemistry, computational methods, and toxicology can be integrated to better understand complex diseases.
🔬 12 Articles | 🩺 Clinical Research | 🌿 Natural Products | 💊 Pharmacology | 🧬 Genetics | 🌍 Public Health
Together, these contributions reflect the multidisciplinary scope of RABMS and provide perspectives ranging from experimental laboratory research and clinical case reports to public health and emerging approaches in medical science.