Volume 8, Issue 2 (5-2022)
Journal of Research in Applied and Basic Medical Sciences 2022, 8(2): 104-109 |
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Afsharyavari S. Multidrug Resistance among Clinical Isolates of Acinetobacter lwoffii. Journal of Research in Applied and Basic Medical Sciences 2022; 8 (2) :104-109
URL: http://ijrabms.umsu.ac.ir/article-1-111-en.html
URL: http://ijrabms.umsu.ac.ir/article-1-111-en.html
Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Urmia University of Medical Sciences, Urmia, Iran , shafsharyavari@yahoo.com
Abstract: (1258 Views)
Background & Aims: This study has the objective to examine the resistance of the clinical isolates of Acinetobacter lwoffii to antibiotics.
Materials & Methods: The samples, that were isolated from the patients admitted to Gazi Hospital in Turkey, were defined by the MicroScan 5 WalkAway Identification System (Siemens, Germany) in terms of species and were thus collected. Then, the resistance pattern of 10 isolated A.lwoffii strains was assessed to 11 antibodies and four antibiotic compounds in this study.
Results: 50% of the strains were found to be Multidrug-Resistant (MDR). Tigecycline was proved to be the most effective antibiotic with 80% sensitivity and 10% intermediate sensitivity.
Conclusion: The MDR A.lwoffii strains were observed in the clinical isolate of Gazi hospital patients. Hence, the identification and investigation of the model of antibiotic resistance of the microorganisms is necessary.
Materials & Methods: The samples, that were isolated from the patients admitted to Gazi Hospital in Turkey, were defined by the MicroScan 5 WalkAway Identification System (Siemens, Germany) in terms of species and were thus collected. Then, the resistance pattern of 10 isolated A.lwoffii strains was assessed to 11 antibodies and four antibiotic compounds in this study.
Results: 50% of the strains were found to be Multidrug-Resistant (MDR). Tigecycline was proved to be the most effective antibiotic with 80% sensitivity and 10% intermediate sensitivity.
Conclusion: The MDR A.lwoffii strains were observed in the clinical isolate of Gazi hospital patients. Hence, the identification and investigation of the model of antibiotic resistance of the microorganisms is necessary.
Type of Study: orginal article |
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References
1. Rossau R, A Van Landschoot, Gillis M and Deley J. Taxonomy of Moraxellaceae fam. nov., a New Bacterial Family To Accommodate the Genera Moraxella, Acinetobacter, and Psychrobacter and Related Organisms. International Journal of Systematic Bacteriology1991; 41(2): 310-319. [DOI:10.1099/00207713-41-2-310]
2. Beijerink M. Pigmenten als oxydatieproducten gevormd door bacterien. Vers. Konin. Akad Wet. Ams1911; 19: 1092-1103.
3. Bouvet PJ. Grimont PA.Identification and biotyping of clinical isolates of Acinetobacter. Ann Inst Pasteur Microbiol 1987; 138(5): 569-578. [DOI:10.1016/0769-2609(87)90042-1] [PMID]
4. Lessel E. F. International Committee on Nomenclature of Bacteria: Subcommittee on the Taxonomy of Moraxella and Allied Bacteria. International Journal of Systematic Bacteriology1971; 21(2): 213-214. [DOI:10.1099/00207713-21-2-213]
5. Towner K. J.Acinetobacter: an old friend, but a new enemy. J Hosp Infect 2009; 73(4): 355-363. [DOI:10.1016/j.jhin.2009.03.032] [PMID]
6. Nemec A, Radolfová-Křížová L, Maixnerová M, Shestivska V, Španělová P, Higgins PG. Acinetobacter silvestris sp. nov. discovered in forest ecosystems in Czechia. International Journal of Systematic and Evolutionary Microbiology [Internet]. 2022 Apr 21 [cited 2022 Jul 19];72(4). Available from: https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.005383 [DOI:10.1099/ijsem.0.005383] [PMID]
7. Almasaudi SB. Acinetobacter spp. as nosocomial pathogens: Epidemiology and resistance features. Saudi J Biol Sci. 2018; 25(3):586-596. [DOI:10.1016/j.sjbs.2016.02.009] [PMID] [PMCID]
8. Espinal P,Roca I and Vila J.Clinical impact and molecular basis of antimicrobial resistance in non-baumannii Acinetobacter. Future Microbiol. 2011; 6(5): 495-511. [DOI:10.2217/fmb.11.30] [PMID]
9. Roy R, Das D, Kumar S, and Mukherjee A. Postcataract Surgery Endophthalmitis Caused by Acinetobacter Lwoffii. Middle East Afr J Ophthalmol 2015; 22(2): 253-254. [DOI:10.4103/0974-9233.151974] [PMID] [PMCID]
10. Regalado NG, Martin G, Antony SJ.Acinetobacter lwoffii. Bacteremia associated with acute gastroenteritis. Travel Med Infect Di. 2009; 7, 316-331. [DOI:10.1016/j.tmaid.2009.06.001] [PMID]
11. Huddam B, Kocak G, Azak A, and Duranay M. Acinetobacter lwoffii Peritonitis in a Patient Receiving Continuous Ambula tory Peritoneal Dialysis, Ther Apher Dial. 2013; 17(1), 117-119. [DOI:10.1111/j.1744-9987.2012.01099.x] [PMID]
12. Pal Singh N, Sagar T, Nirmal K and Rajender Kaur I.Pyogenic liver abscess caused by acinetobacter Lwoffii: A case report.Journal of Clinical and Diagnostic Research 2016; 10(6), DD01-DD02. [DOI:10.7860/JCDR/2016/18256.7943] [PMID] [PMCID]
13. Toyoshima M, Chida K and Suda T.Fulminant community-acquired pneumonia probably caused by Acinetobacter lwoffii Respirology 2010; 15(5), 867-8680 [DOI:10.1111/j.1440-1843.2010.01780.x] [PMID]
14. Rathinavelu S , Zavros Y , Merchant JL.Acinetobacter lwoffıi infection and gastritis. Microbes Infect 2003;5(7), 651-657. [DOI:10.1016/S1286-4579(03)00099-6] [PMID]
15. Na S, Jun WY, Qin ZS, Wei ZH, Guo Li, Xue WF and et al.Detection of Multi-drug Resistant Acinetobacter lwoffii Isolated from Soil of Mink Farm. Biomed Environ Sci 2016; 29(7): 521-523. [Google Scholar]
16. Wang Y, Wu C, Zhang Q,Qi J,Liu H,Wang Y and et al. Identification of New Delhi metallo-beta lactamase 1 in Acinetobacter lwoffii of food animal origin. PLoS One 2012; 7(5), e 37152. [DOI:10.1371/journal.pone.0037152] [PMID] [PMCID]
17. Kozińska A, Paździor E, Pękala A, Niemczuk W. Acinetobacter johnsonii and Acinetobacter lwoffii - the emerging fish pathogens. Bull Vet Inst Pulawy 2014; 58,193-199. [DOI:10.2478/bvip-2014-0029]
18. Ku SC, Hsueh PR, Yang PC, Luh KT. Clinical and microbiological characteristic of bacteremia caused by Acinetobacter lwoffii. Eur J Clin Microbiol Infect Dis 2000; 19:501-505. [DOI:10.1007/s100960000315] [PMID]
19. Dadar M, Adel M, Zorriehzahra MJ. Isolation and phylogenic analysis of emerging new antibiotic resistant bacteria, Acinetobacter lwoffii, associated with mortality in farmed rainbow trout .Iranian Journal of Fisheries Sciences 2016;15(4) 1279-1292. [Google Scholar]
20. Engin A. Acinetobacter-associated nosocomial infections in Cumhuriyet University Medical Faculty Research Hospital: Three years' experience. Cumhur Medical J 2017; 39(3), 555-563. [DOI:10.7197/223.v39i31705.347454]
21. Tega L, Raieta K, Ottaviani D, Russo GL, Blanco G, Carraturo A. Catheter-related bacteremia and multidrug- resistant acinetobacterlwoffii. Emerg Infect Dis 2007; 13:355-356. [DOI:10.3201/eid1302.060858] [PMID] [PMCID]
22. Larson E,Cimiotti J, Haas J, Nesin M, Allen A, Della-Latta P, Saiman L. Gram-negative bacilli associated with catheter-associated and non-catheter-associated bloodstream infections and hand carriage by healthcare workers in neonatal intensive care units. Pediatr Crit Care Med 2005; 6(4):457-461. [DOI:10.1097/01.PCC.0000163669.37340.91] [PMID]
23. Singla P, Sikka R, Deeep A, et al. Co-production of ESBL and AmpC beta-Lactamases in Clinical Isolates of A. baumannii and A. lwoffii in a Tertiary Care Hospital from Northern India. J Clin Diagn Res 2014; 8(4), 16-19. [DOI:10.7860/JCDR/2014/8008.4289] [PMID] [PMCID]
24. Mittal S, Sharma M, Yadav ABala K,Chaudhary U. Acinetobacter lwoffii an emerging pathogen in neonatal ICU. Infect Disord Drug Targets 2015; 15(3), 184-188. [DOI:10.2174/1871526515666150826114745] [PMID]
25. Amirmozafari N.,Forouhesh Taheri H.,Mohebbi S.Survey Genus and Species of Non-Fermentative Gram Negative Bacilli Isolated From Hospitalized Patients. J Guilan Univ Med Sci 2007; 16)64(, 67-75. [Google Scholar]
26. Babapour E, Haddadi A, Mirnejad R, Angaji SA, Amirmozafari N. Study of drug resistance and ompA gene existence in clinical Acinetobacter baumannii isolates. Iran J Med Microbiol2017; 11(1) [Google Scholar]
27. Vahedi A, Baghani A, Baseri Z, Pourmand MR. Frequency and antibiotic resistance patterns of isolated bacteria from positive blood culture of hospitalized patients Tehran Univ Med J 2018; 75(12): 902-912. [Google Scholar]
28. Nakwan N, Wannaro J, Nakwan N. Multidrug-resistant Acinetobacter lwoffii infection in neonatal intensive care units. Res Rep Neonatol 2011; 1, 1-4. [DOI:10.2147/RRN.S15964]
29. Ozdem B, Gurelik FC, Çelikbilek N, Balikci H, Acikgoz ZC.Antibiotic Resistance Profiles of Acinetobacter Species Isolated from Several Clinical Samples Between 2007-2010; Mikrobiyol Bul 2011; 45: 526-534. [Google Scholar]
30. Wei WJ, Yang HF, Ye Y, Li JB.New Delhi Metallo-β-Lactamase-Mediated Carbapenem Resistance: Origin, Diagnosis, Treatment and Public Health Concern.Chin Med J 2015;128(14):1969-1976. [DOI:10.4103/0366-6999.160566] [PMID] [PMCID]
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