The Role of Radioprotector Agents in the Protection of Normal tissue

Emamgholizadeh Minaei, Soraya; Hoseini, Farideh

doi:10.52547/rabms.7.3.161

Volume 7, Issue 3 (12-2021) Journal of Research in Applied and Basic Medical Sciences 2021, 7(3): 161-171 | Back to browse issues page

‎ 10.52547/rabms.7.3.161

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Emamgholizadeh Minaei S, Hoseini F. The Role of Radioprotector Agents in the Protection of Normal tissue. Journal of Research in Applied and Basic Medical Sciences 2021; 7 (3) :161-171
URL: http://ijrabms.umsu.ac.ir/article-1-115-en.html

The Role of Radioprotector Agents in the Protection of Normal tissue

Soraya Emamgholizadeh Minaei ^*

, Farideh Hoseini

Department of Medical Physics and Imaging, Urmia University of Medical Sciences, Urmia, Iran , minayee.s@gmail.com

Abstract: (1665 Views)

The role of radioprotectors to reduce the cellular damage induced by ionizing radiation has been studied in human, animal and in vitro culture models. Radiation therapy cannot eradicate tumors successfully because of soft tissue damage. Proper use of radioprotective agents (before or shortly after radiation) can reduce normal tissue radiation toxicity and improve treatment output. There are three groups of radioprotectors: Synthetic protectors, antioxidant nutrients, and Immunomodulators. We discussed the radioprotective efficacy and its interaction against toxic agents. In addition, we discussed articles that have used radioprotective agents in the treatment of cancer with radiotherapy to protect normal tissue.

Keywords: Radio protectors, Free radical, Antioxidant, Toxic substances, Radical scavenger

Full-Text [PDF 444 kb] (1103 Downloads)

Type of Study: review article | Subject: General

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