An overview of monkeypox: let’s be aware of the emerging yet underreported disease

Husain, Uneza; Priyadarshi, Ketan

doi:10.61186/rabms.10.3.240

Volume 10, Issue 3 (7-2024) Journal of Research in Applied and Basic Medical Sciences 2024, 10(3): 240-244 | Back to browse issues page

‎ 10.61186/rabms.10.3.240

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Husain U, Priyadarshi K. An overview of monkeypox: let’s be aware of the emerging yet underreported disease. Journal of Research in Applied and Basic Medical Sciences 2024; 10 (3) :240-244
URL: http://ijrabms.umsu.ac.ir/article-1-324-en.html

An overview of monkeypox: let’s be aware of the emerging yet underreported disease

Uneza Husain ^*

, Ketan Priyadarshi

Assistant Professor, Department of Microbiology, Government Doon Medical College, Dehradun, Uttarakhand, India , uneza47@gmail.com

Abstract: (743 Views)

Background & Aims: A lot is being heard regarding monkeypox, which is currently an emerging disease. The sole purpose of this publication is to enlighten the world regarding epidemiology in the context of recent outbreaks, etiopathogenesis, clinical features, diagnosis, and management, depicting an overview of this underreported disease so that the concerned microbiologists and clinicians can diagnose and manage the disease as soon as possible.
Materials & Methods: In this review study, we searched Google Scholar, PubMed, and Scopus databases to keywords regarding the main objective of the study, and collected the most recent and novel studies less than 10 years about the objectives of the study.
Results: Recent outbreaks, etiopathogenesis, clinical features, diagnosis, and management, depicting Monkeypox were collected and categorized to highlight the importance of the disease in recent communities.
Conclusion: Although and underreported disease, Monkeypox is a disease with important effects in today's societies, and it is needed that health officials be aware of its importance and have programs to control it. With improved knowledge, monitoring of the exposed cases, and better infrastructure, we can successfully contain this emerging and potentially re-emerging viral disease.

Keywords: Monkeypox, Mpox, Pox-Like Disease, Virus, Zoonotic

Full-Text [PDF 249 kb] (395 Downloads) | | Full-Text (HTML) (82 Views)

Type of Study: review article | Subject: Virology

References

1. Von Magnus P, Anderson E.K, Petersen K.B, Birch-Andersen A. A pox-like disease in cynomolgus monkeys. Acta Pathol Microbiol Scand 1959;46:156-76. [DOI:10.1111/j.1699-0463.1959.tb00328.x]

2. Cheema AY, Ogedegbe OJ, Munir M, Alugba G, Ojo TK. Monkeypox: A Review of Clinical Features, Diagnosis, and Treatment. Cureus 2022;14(7):e26756. [DOI:10.7759/cureus.26756]

3. Poland GA, Kennedy RB, Tosh PK. Prevention of monkeypox with vaccines: a rapid review. Lancet Infect Dis 2022;22(12):e349-e58. [DOI:10.1016/S1473-3099(22)00574-6] [PMID]

4. World Health Organization.Monkeypox.2022; https://www.who.int/news-room/fact-sheets/detail/monkeypox [URL]

5. Soheili M, Nasseri S, Afraie M, Khateri S, Moradi Y, Mortazavi SM, et al. Monkeypox: Virology, Pathophysiology, Clinical Characteristics, Epidemiology, Vaccines, Diagnosis, and Treatments. J Pharm Pharm Sci 2022;25:297-322. [DOI:10.18433/jpps33138] [PMID]

6. Ogoina D, Izibewule JH, Ogunleye A, Ederiane E, Anebonam U, Neni A, et al. The 2017 human monkeypox outbreak in Nigeria-Report of outbreak experience and response in the Niger Delta University Teaching Hospital, Bayelsa State, Nigeria. PLoS One 2019;14(4):e0214229. [DOI:10.1371/journal.pone.0214229] [PMID] []

7. Titanji BK, Tegomoh B, Nematollahi S, Konomos M, Kulkarni PA. Monkeypox: A Contemporary Review for Healthcare Professionals. Open Forum Infect Dis 2022;9(7):ofac310. [DOI:10.1093/ofid/ofac310] [PMID] []

8. Kozlov M. Monkeypox declared a global emergency: will it help contain the outbreak? Nature 2022. http://dx.doi.org/10.1038/d41586-022-02054-7 [DOI:10.1038/d41586-022-02054-7]

9. Desingu PA, Rubeni TP, Sundaresan NR. Evolution of monkeypox virus from 2017 to 2022: In the light of point mutations. Front Microbiol 2022;13:1037598. [DOI:10.3389/fmicb.2022.1037598] [PMID] []

10. Hammarlund E, Dasgupta A, Pinilla C, Norori P, Fruh K, Slifka MK. Monkeypox virus evades antiviral CD4+ and CD8+ T cell responses by suppressing cognate T cell activation. Proc Natl Acad Sci U S A 2008;105(38):14567-72. [DOI:10.1073/pnas.0800589105] [PMID] []

11. Huang Y, Mu L, Wang W. Monkeypox: epidemiology, pathogenesis, treatment, and prevention. Signal Transduct Target Ther 2022;7(1):373. [DOI:10.1038/s41392-022-01215-4] [PMID] []

12. Adler H, Gould S, Hine P, Snell LB, Wong W, Houlihan CF, et al. Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis 2022;22(8):1153-62. [DOI:10.1016/S1473-3099(22)00228-6] [PMID]

13. Centers for Disease Control and Prevention. Case Definitions† for Use in the 2022 Mpox Response 2022. https://www.cdc.gov/poxvirus/monkeypox/clinicians/case-definition.html [URL]

14. Nolen LD, Osadebe L, Katomba J, Likofata J, Mukadi D, Monroe B, et al. Extended Human-to-Human Transmission during a Monkeypox Outbreak in the Democratic Republic of the Congo. Emerg Infect Dis 2016;22(6):1014-21. [DOI:10.3201/eid2206.150579] [PMID] []

15. Perzia B, Theotoka D, Li K, Moss E, Matesva M, Gill M, et al. Treatment of ocular-involving monkeypox virus with topical trifluridine and oral tecovirimat in the 2022 monkeypox virus outbreak. Am J Ophthalmol Case Rep 2023;29:101779. [DOI:10.1016/j.ajoc.2022.101779] [PMID] []