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Abbasi M A, Rikhtegar E, Keshtkar Rajabi S. An Interesting Case with Extrapulmonary Manifestations of Sarcoidosis. Journal of Research in Applied and Basic Medical Sciences 2023; 9 (3) :138-142
URL: http://ijrabms.umsu.ac.ir/article-1-239-en.html
Firoozabadi hospital clinical research development unit (FHCRDU), Department of internal medicine, school of medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran , sh_rajabi64@yahoo.com
Abstract:   (599 Views)
Sarcoidosis is characterized by a various courses and clinical presentation and in this era, some patients may have some symptoms difficult to establish the sarcoidosis diagnosis. Here we report a new case of sarcoidosis with some learning points for the clinicians. We report a 39-year-old male patient attending to the clinic due to productive cough, dyspnea, and skin lesions as papule as well as erythematous plaques in extensor regions of elbows and knees. Regarding the biopsy results of skin lesions, hillar, mediastinal lymphadenopathy, and serum ACE level the sarcoidosis was proposed. Fatigue, spinal pain, and paraplegia plus paraparesis of lower limb, tachycardia, multiple lesions at the lumbar spine, skin lesions, and posterior fossa toxoplasmosis were the findings at later visits, representing a confusing course. Finally, according to the presentation of the case reported in this paper, we concluded that the patients with sarcoidosis may present with multiple extrapulmonary manifestations that would result in some confusing points for diagnosis. Prompt clinical and imaging assessment would result in faster diagnosis and better prognosis to decrease the burden of disease.
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Type of Study: case report | Subject: Special

1. Valeyre D, Prasse A, Nunes H, Uzunhan Y, Brillet PY, Müller-Quernheim J. Sarcoidosis. Lancet 2014;383(9923):1155-67. https://doi.org/10.1016/S0140-6736(13)60680-7 [DOI:10.1016/s0140-6736(13)60680-7] [PMID]
2. Margolis R, Lowder CY. Sarcoidosis. Curr Opin Ophthalmol 2007;18(6):470-5. [DOI:10.1097/ICU.0b013e3282f06c6c] [PMID]
3. Mortaz E, Masjedi MR, Tabarsi P, Pourabdollah M, Adcock IM. Immunopathology of sarcoidosis. Iran J Allergy Asthma Immunol 2014;13(5):300-6. [Google Scholar]
4. Baughman RP, Lower EE, du Bois RM. Sarcoidosis. Lancet 2003;361(9363):1111-8. https://doi.org/10.1016/S0140-6736(03)12888-7 [DOI:10.1016/s0140-6736(03)12888-7] [PMID]
5. Wessendorf TE, Bonella F, Costabel U. Diagnosis of Sarcoidosis. Clin Rev Allergy Immunol 2015;49(1):54-62. [DOI:10.1007/s12016-015-8475-x] [PMID]
6. Valeyre D, Bernaudin JF, Uzunhan Y, et al. Clinical presentation of sarcoidosis and diagnostic work-up. Semin Respir Crit Care Med 2014;35(3):336-51. [DOI:10.1055/s-0034-1381229] [PMID]
7. Morgenthau AS, Iannuzzi MC. Recent advances in sarcoidosis. Chest 2011;139(1):174-82. [DOI:10.1378/chest.10-0188] [PMID]
8. Baughman RP, Culver DA, Judson MA. A concise review of pulmonary sarcoidosis. Am J Respir Crit Care Med 2011;183(5):573-81. https://doi.org/10.1164/rccm.201006-0865CI [DOI:10.1164/rccm.201006-0865ci] [PMID] []
9. Reddy RR, Shashi Kumar BM, Harish MR. Cutaneous sarcoidosis - a great masquerader: a report of three interesting cases. Indian J Dermatol 2011;56(5):568-72. [DOI:10.4103/0019-5154.87158] [PMID] []
10. Gautam M, Patil S, Munde P. Skin as a marker of internal disease: a case of sarcoidosis. Indian J Dermatol 2011;56(4):439-41. [DOI:10.4103/0019-5154.84756] [PMID] []
11. Giovinale M, Fonnesu C, Soriano A, et al. Atypical sarcoidosis: case reports and review of the literature. Eur Rev Med Pharmacol Sci 2009;13(1):37-44. [PMID]
12. Silva JR, Correia E, Gama P, Nascimento C, Dionísio O, Santos O. Cardiac sarcoidosis: a case report. Rev Port Cardiol 2008;27(9):1147-54. [PMID]
13. Kaur G, Cameron L, Syritsyna O, Coyle P, Kowalska A. A Case Report of Neurosarcoidosis Presenting as a Lymphoma Mimic. Case Rep Neurol Med 2016;2016:7464587. [DOI:10.1155/2016/7464587] [PMID] []
14. Fahoum F, Drory VE, Issakov J, Neufeld MY. Neurosarcoidosis presenting as Guillain-Barré-like syndrome. A case report and review of the literature. J Clin Neuromuscul Dis 2009;11(1):35-43. https://doi.org/10.1097/CND.0b013e3181ae3be9 [DOI:10.1097/cnd.0b013e3181ae3be9] [PMID]
15. Findik S, Bulbul R, Ozbenli T, et al. Sarcoidosis and Gullain-Barré syndrome. Acta Neurol Belg 2011;111(1):72-5. [Google Scholar]
16. Takahashi Y, Izumi C, Miyake M, Nakajima S, Nishimura S, Kuroda M, et al. Detecting Cardiac Sarcoidosis with a Right Atrial Mass Using Transthoracic Echocardiography. Intern Med 2016;55(4):359-63. [DOI:10.2169/internalmedicine.55.5423] [PMID]
17. Bertic M, Tandon S, Wisenberg G. Right ventricular mass: a rare presentation of cardiac sarcoidosis. Eur Heart J 2016;37(11):859. [DOI:10.1093/eurheartj/ehv660] [PMID] []
18. Abrishami B, O'Connel C, Sharma O. Cardiac sarcoidosis with presentation of large left atrial mass. Curr Opin Pulm Med 2004;10(5):397-400. [DOI:10.1097/01.mcp.0000136403.32451.aa] [PMID]

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